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Dr. Carlos M. De Castro III, MD

Accepting New Patients

(Dr. Carlos Manuel Decastro III, M.D.)

(379 Ratings)

Specializes in: Adult Oncology and Adult Hematology

University of Texas Southwestern Medical School (1985)

Professional interests include: hairy cell leukemia, acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and more.

20 Duke Medicine Circle
Durham, NC 27710

(919) 681-6900

Dr. Carlos M. De Castro III, MD is an oncologist in Durham, NC specializing in adult oncology and adult hematology. He graduated from University of Texas Southwestern Medical School in 1985 and has 41 years of experience. Dr. Carlos M. De Castro III, MD is affiliated with Duke Health and DUKE HEALTH INTEGRATED PRACTICE INC.

Office Locations

Duke Health

20 Duke Medicine Circle
Durham, NC 27710

(919) 681-6900

open_in_new

2400 Pratt Street
Durham, NC 27705

open_in_new

Duke University Medical Center
Durham, NC 27710

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Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2012 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

aspiration	26
bone marrow tests	52
diagnostic procedures	52
doctor visit	658
hospital care	682
inpatient care	663
outpatient care	19

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2013 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

bone marrow tests	15
diagnostic procedures	15
doctor visit	585
hospital care	570
inpatient care	570

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	153
Female	162

**Ethnicity**
Non-Hispanic White	247
Black	54
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	146
From 75 to 84	97
85 and over	24
Less than 65	48

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2013

Hypertension	63
High Cholesterol	52
Stroke	5
Ischemic Heart Disease	35
Depression	21
Chronic Kidney Disease	39
Asthma	5
Osteoperosis	7
Atrial Fibrilation	13
Heart Failure	19
Chronic Obstructive Pulmonary Disease	12
Diabetes	27
Dementia	4
Cancer	10

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2014 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

bone marrow tests	18
diagnostic procedures	18
doctor visit	537
hospital care	642
inpatient care	642

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	162
Female	146

**Ethnicity**
Non-Hispanic White	238
Black	57
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	143
From 75 to 84	94
85 and over	26
Less than 65	45

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2014

Hypertension	65
High Cholesterol	52
Stroke	7
Ischemic Heart Disease	34
Depression	23
Chronic Kidney Disease	36
Asthma	6
Osteoperosis	8
Atrial Fibrilation	13
Heart Failure	20
Chronic Obstructive Pulmonary Disease	14
Diabetes	31
Dementia	7
Cancer	11

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2015 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

aspiration	29
bone marrow tests	60
diagnostic procedures	60
doctor visit	686
hospital care	510
inpatient care	510

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	352
Female	254

**Ethnicity**
Non-Hispanic White	470
Black	110
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	282
From 75 to 84	184
85 and over	58
Less than 65	82

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2015

Hypertension	68
High Cholesterol	54
Stroke	7
Ischemic Heart Disease	33
Depression	24
Chronic Kidney Disease	40
Asthma	11
Osteoperosis	7
Atrial Fibrilation	17
Heart Failure	25
Chronic Obstructive Pulmonary Disease	14
Diabetes	33
Dementia	6
Cancer	11

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2016 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

aspiration	23
bone marrow tests	46
diagnostic procedures	46
doctor visit	705
hospital care	490
inpatient care	490

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	158
Female	155

**Ethnicity**
Non-Hispanic White	250
Black	48
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	138
From 75 to 84	101
85 and over	27
Less than 65	47

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2016

Hypertension	71
High Cholesterol	49
Stroke	5
Ischemic Heart Disease	31
Depression	25
Chronic Kidney Disease	48
Asthma	17
Osteoperosis	7
Atrial Fibrilation	17
Heart Failure	25
Chronic Obstructive Pulmonary Disease	17
Diabetes	29
Dementia	10
Cancer	15

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2017 were hospital care, inpatient care, diagnostic procedures and bone marrow tests.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

aspiration	29
bone marrow tests	58
diagnostic procedures	58
doctor visit	682
hospital care	391
inpatient care	391

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	183
Female	135

**Ethnicity**
Non-Hispanic White	262
Black	43
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	137
From 75 to 84	112
85 and over	28
Less than 65	41

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2017

Hypertension	66
High Cholesterol	48
Stroke	0
Ischemic Heart Disease	37
Depression	29
Chronic Kidney Disease	43
Asthma	7
Osteoperosis	5
Atrial Fibrilation	14
Heart Failure	21
Chronic Obstructive Pulmonary Disease	16
Diabetes	30
Dementia	10
Cancer	15

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2018 were hospital care and inpatient care.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

doctor visit	665
hospital care	416
inpatient care	416

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	172
Female	130

**Ethnicity**
Non-Hispanic White	247
Black	41
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	142
From 75 to 84	104
85 and over	26
Less than 65	30

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2018

Hypertension	69
High Cholesterol	56
Stroke	5
Ischemic Heart Disease	36
Depression	22
Chronic Kidney Disease	42
Asthma	7
Osteoperosis	6
Atrial Fibrilation	15
Heart Failure	22
Chronic Obstructive Pulmonary Disease	12
Diabetes	28
Dementia	14
Cancer	16

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2019 were hospital care and inpatient care.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

doctor visit	545
hospital care	284
inpatient care	284

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	144
Female	118

**Ethnicity**
Non-Hispanic White	206
Black	40
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	116
From 75 to 84	98
85 and over	24
Less than 65	24

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2019

Hypertension	71
High Cholesterol	57
Stroke	5
Ischemic Heart Disease	42
Depression	24
Chronic Kidney Disease	46
Asthma	6
Osteoperosis	7
Atrial Fibrilation	13
Heart Failure	22
Chronic Obstructive Pulmonary Disease	10
Diabetes	28
Dementia	10
Cancer	13

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2020 were hospital care and inpatient care.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

doctor visit	446
hospital care	169
inpatient care	169

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	120
Female	98

**Ethnicity**
Non-Hispanic White	170
Black	32
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	89
From 75 to 84	91
85 and over	19
Less than 65	19

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2020

Hypertension	70
High Cholesterol	63
Stroke	7
Ischemic Heart Disease	38
Depression	26
Chronic Kidney Disease	46
Asthma	7
Osteoperosis	7
Atrial Fibrilation	12
Heart Failure	24
Chronic Obstructive Pulmonary Disease	12
Diabetes	28
Dementia	11
Cancer	18

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2021 were hospital care and inpatient care.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

doctor visit	471
hospital care	296
inpatient care	296

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	116
Female	93

**Ethnicity**
Non-Hispanic White	168
Black	27
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	89
From 75 to 84	86
85 and over	17
Less than 65	17

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2021

Hypertension	74
High Cholesterol	60
Stroke	8
Ischemic Heart Disease	36
Depression	22
Chronic Kidney Disease	49
Asthma	5
Osteoperosis	9
Atrial Fibrilation	16
Heart Failure	25
Chronic Obstructive Pulmonary Disease	14
Diabetes	30
Dementia	11
Cancer	19

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC during 2022 were hospital care and inpatient care.

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

doctor visit	411
hospital care	293
inpatient care	293

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	114
Female	85

**Ethnicity**
Non-Hispanic White	158
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	82
From 75 to 84	79
85 and over	20
Less than 65	18

Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD in 2022

Hypertension	75
High Cholesterol	72
Stroke	12
Ischemic Heart Disease	29
Depression	24
Chronic Kidney Disease	33
Asthma	11
Osteoperosis	13
Atrial Fibrilation	28
Heart Failure	25
Chronic Obstructive Pulmonary Disease	16
Diabetes	34
Dementia	12
Cancer	20

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. Carlos M. De Castro III, MD for Medicare patients.

The highest averages for the top procedures that Dr. Carlos M. De Castro III, MD treated as an oncologist in Durham, NC were hospital care, inpatient care, bone marrow tests and diagnostic procedures.

aspiration	26
bone marrow tests	41
diagnostic procedures	41
doctor visit	581
hospital care	431
inpatient care	429
outpatient care	19

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. Carlos M. De Castro III, MD.

**Gender**
Male	152
Female	125

**Ethnicity**
Black / African American	41
Asian / Pacific Islander	0
Non-Hispanic White	219
Native American / Alaskan Native	0
Hispanic	0
Other	0

**Age**
75 to 84	95
85 and over	24
Less than 65	33
65 to 74	124

Average of Total of Conditions of Medicare patients treated by Dr. Carlos M. De Castro III, MD From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Carlos M. De Castro III, MD treated were hypertension, high cholesterol, chronic kidney disease and ischemic heart disease.

Hypertension	62
High Cholesterol	51
Stroke	5
Ischemic Heart Disease	31
Depression	21
Chronic Kidney Disease	38
Asthma	7
Osteoporosis	6
Heart Failure	20
Chronic Obstructive Pulmonary Disease	12
Diabetes	27
Atrial Fibrillation	14
Dementia	8
Cancer	13

Education & Training

Dr. Carlos M. De Castro III, MD graduated from University of Texas Southwestern Medical School in 1985. He completed residency at Parkland Health & Hospital System. He is certified by the American Board of Internal Med, Internal Medicine and has a state license in North Carolina.

Medical School: University of Texas Southwestern Medical School (1985)

Residency: Parkland Health & Hospital System (1988)

Board Certification: American Board of Internal Med, Internal Medicine

Licensed In: North Carolina

Affiliations & Hospitals

Dr. Carlos M. De Castro III, MD is associated with these hospitals and organizations:

Duke Health

DUKE HEALTH INTEGRATED PRACTICE INC

Insurance Information

Please note: Insurance information may change at any time, and the provider may accept your insurance plan even if it is not listed below. Please contact the provider's office to confirm that your insurance is accepted.

Dr. Carlos M. De Castro III, MD appears to accept the following insurance providers: MedCost, Aetna Traditional Choice, Aetna Medicare PPO, BlueCross BlueShield of North Carolina, CIGNA Open Access Plus, WellCare, AmeriHealth, Medicare Part B, Medicare Advantage, AARP, CIGNA Open Access, United Healthcare PPO, United Healthcare POS, United Healthcare HMO, Aetna, Aetna Workers' Compensation, TRICARE Prime, United Healthcare, Aetna Open Choice PPO, TRICARE Prime Remote, Medicare, Medicaid, Humana, Cigna, TRICARE, Harvard Pilgrim Health Care, Aetna Managed Choice POS, Gateway Health Alliance, Aetna HMO, Alliance Health (*Beginning January 2026), *Duke HomeCare and Hospice does not participate in the plan., Duke Employee Plans, Blue Options (123, PPO, HSA), *Duke HomeCare and Hospice and mental health providers do not participate with the plan., Aetna Quality Point of Service (QPOS), Aetna Choice POS, Aetna Choice POS II, Duke Advantage (*Beginning January 2026), Aetna Medicare Value Plan (HMO), Blue Advantage (*Available in select counties only), Duke Options (*Beginning January 2026), Duke Basic, Duke USA (*Beginning January 2026), Ambetter, Experience Health, Aetna Select HMO, Aetna PCP Coordinated POS Plan, Blue Select, Blue Medicare (HMO, PPO)*, Aetna Limited Benefit Insurance PPO, Vaya Health (*Beginning January 2026), Healthy Blue, Trillium (*Beginning January 2026), Aetna Health Network Only, Aetna Health Network Option, All Savers Fully Insured, Blue Value (*Duke Health Lake Norman and Kernodle Clinics only), First Medicare Direct, Carolina Complete Health, Healthgram, All Savers Alternate Funding, Aetna Medicare Assure Plan (HMO D-SNP), Aetna/CVS Health, Aetna Elect Choice HMO, Aetna Open Access Elect Choice, Partners (*Beginning January 2026), Aetna Voluntary Indemnity Group Plan, Duke Select, Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice, NC State Employees Health Plan, Ambetter of North Carolina and United Medical Resources (UMR).

Insurance Accepted by Provider includes:

According to our sources, Dr. Carlos M. De Castro III, MD accepts the following insurance providers:

MedCost

Aetna Traditional Choice

Aetna Medicare PPO

BlueCross BlueShield of North Carolina

CIGNA Open Access Plus

WellCare

AmeriHealth

Medicare Part B

Medicare Advantage

AARP

CIGNA Open Access

United Healthcare PPO

United Healthcare POS

United Healthcare HMO

Aetna

Aetna Workers' Compensation

TRICARE Prime

United Healthcare

Aetna Open Choice PPO

TRICARE Prime Remote

Medicare

Medicaid

Humana

Cigna

TRICARE

Harvard Pilgrim Health Care

Aetna Managed Choice POS

Gateway Health Alliance

Aetna HMO

Alliance Health (*Beginning January 2026)

*Duke HomeCare and Hospice does not participate in the plan.

Duke Employee Plans

Blue Options (123, PPO, HSA)

*Duke HomeCare and Hospice and mental health providers do not participate with the plan.

Aetna Quality Point of Service (QPOS)

Aetna Choice POS, Aetna Choice POS II

Duke Advantage (*Beginning January 2026)

Aetna Medicare Value Plan (HMO)

Blue Advantage (*Available in select counties only)

Duke Options (*Beginning January 2026)

Duke Basic

Duke USA (*Beginning January 2026)

Ambetter

Experience Health

Aetna Select HMO

Aetna PCP Coordinated POS Plan

Blue Select

Blue Medicare (HMO, PPO)*

Aetna Limited Benefit Insurance PPO

Vaya Health (*Beginning January 2026)

Healthy Blue

Trillium (*Beginning January 2026)

Aetna Health Network Only, Aetna Health Network Option

All Savers Fully Insured

Blue Value (*Duke Health Lake Norman and Kernodle Clinics only)

First Medicare Direct

Carolina Complete Health

Healthgram

All Savers Alternate Funding

Aetna Medicare Assure Plan (HMO D-SNP)

Aetna/CVS Health

Aetna Elect Choice HMO, Aetna Open Access Elect Choice

Partners (*Beginning January 2026)

Aetna Voluntary Indemnity Group Plan

Duke Select

Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice

NC State Employees Health Plan

Ambetter of North Carolina

United Medical Resources (UMR)

Ratings & Reviews

Dr. Carlos M. De Castro III, MD has an exceptional overall rating with an average of 4.87 out of 5 stars based on 379 ratings. We collect ratings and reviews of Dr. Carlos M. De Castro III, MD from all over the web to help you find the right in Durham, NC.

4.87

Overall Rating

(379 Ratings)

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General Payments

These charts describe general payments received by Dr. Carlos M. De Castro III, MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Alexion Pharmaceuticals, Inc.	$49,223 ULTOMIRIS $31,231	SOLIRIS $322	$17,669
Apellis Pharmaceuticals, Inc.	$15,507 Empaveli $15,507
Taiho Oncology, Inc.	$5,938 INQOVI $4,062	$1,875
Genentech, Inc.	$5,846 $5,846
E.R. Squibb & Sons, L.L.C.	$5,536 $5,536
Other	$11,692 TIBSOVO $3,840	Reblozyl $197	BESPONSA $11	$7,644

**Types of Payments**
Consulting Fee	$43,448
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program	$38,642
Honoraria	$6,430
Travel and Lodging	$3,677
Food and Beverage	$1,435
Other	$110

Research Payments

Dr. Carlos M. De Castro III, MD has received 60 research payments totaling $329,732.

Biography

Dr. Carlos Decastro's areas of specialization are adult hematology and adult oncology. Dr. Decastro graduated from the University of Texas Southwestern Medical School. He trained at Parkland Health & Hospital System for residency. In his practice, he is particularly interested in chronic myeloid leukemia (CML), hairy cell leukemia, and chronic lymphocytic leukemia (CLL). Dr. Decastro's average patient rating is 5.0 stars (out of 5). Blue California, CIGNA Plans, and TRICARE are among the insurance carriers that Dr. Decastro honors. He is affiliated with Duke Health. He welcomes new patients at his office inDurham, NC as reported by Duke Health.